Nitrazepam has actually been affiliated with intense hepatic Conditions, comparable to other nitrobenzodiazepines. Nitrobenzodiazepines which include nitrazepam, nimetazepam, flunitrazepam, and clonazepam tend to be more toxic towards the liver than other benzodiazepines as They're metabolically activated by CYP3A4 which may lead to cytotoxicity.In